Prediction of RNA 3D Structure

Research Area: Volume 7,Issue 1, Jan. 2018 Year: 2018
Type of Publication: Article Keywords: RNA, Base Pair, Kissing Pair, Tertiary Structure
Authors:
  • Mrs. Ujjwala H. Mandekar
  • Dr. S. P. Khandait
Journal: IJEIR Volume: 7
Number: 1 Pages: 9-14
Month: January
ISSN: 2277-5668
Abstract:
RNA structures are generally organized hierarchically organized. Prediction of RNA structure is a big challenge for the researchers. Many prediction algorithms have been develop for RNA secondary structure prediction. But prediction of tertiary structure is still a big area of research. Approaches for RNA tertiary structure prediction are broadly categorized into two methods viz. de novo methods and template-based prediction method. The De novo are useful only for the small sequences of the nucleotides. For the sequences with large number of nucleotides template based modelling technique is more useful. These template based method are very common in protein structure prediction but it is not explored in RNA tertiary structure prediction. This paper presents a novel methodology for prediction of RNA tertiary structure using the bank ok known structure (template). First, the RNA secondary structure is analysed on the basis of free nucleotides available region wise which may contribute in the prediction of tertiary structure. Next similar region structure templates are searched in PDB metadata. These templates are then used to for the tertiary structure. As all the templates stored in PDB are predicted structures with minimum negative energy, the resultant tertiary structure is also consequently has minimum negative energy. The proposed method is able to predict even large ribosomal RNA structures. The experimental results have shown for the predicted structures on the basis of percentage similarity as well as time required for prediction.

Indexed By:

Our Journals

IJECCE
International Journal of Electronics Communication and Computer Engineering
ISSN(Online): 2249 - 071X
ISSN (Print) : 2278 – 4209
www.ijecce.org
Submissions open
IJAIR
International Journal of Agriculture Innovations and Research
ISSN(Online) : 2319 – 1473
www.ijair.org
Submissions open
IJISM
International Journal of Innovation in Science and Mathematics
ISSN : 2347 – 9051
www.ijism.org
Submissions open
IJEIR
International Journal of Engineering Innovations and Research
ISSN(Online) : 2277 – 5668
www.ijeir.org
Submissions are open.

IJAIM
International Journal of Artificial Intelligence and Mechatronics
ISSN(Online) : 2320 – 5121
www.ijaim.org
Submissions open
IJRAS
International Journal of Research in Agricultural Sciences
ISSN(Online) : 2348 – 3997
www.ijras.org
Submissions open

Submission Open

"Submissions Open For Volume 8,Issue 6,Nov.- Dec., 2019"

Click here to submit article.........

Latest Updates

Submissions open

Submissions open

For

"Volume 8,Issue 6,Nov.- Dec., 2019"


 
Published Papers

Accepted Papers are published in

1. Recently Published Issue.

"Vol. 8, Issue 5,Sept. - Oct., 2019"


 

Dear Authors

Once author receives paper id, please always mention it in subject of your mail.

"Submissions Open For Volume 8,Issue 6,Nov.- Dec., 2019"

Message for Authors